What are
VITRO-NAILS®?
A Realistic, Highly-Reproducible Substrate for Testing and Optimizing Nail Enamels!

VITRO-NAILS is an advanced testing substrate that effectively mimics the wetting properties, thickness, flexibility and chemical reactivity of human fingernails.

VITRO-NAILS allow rapid evaluation of prototype nail formulations including spreading, dry time, color, gloss, flexibility, durability and resistance to chipping.

VITRO-NAILS let you quickly evaluate your new prototypes versus your current nail products or competitive benchmarks.

VITRO-NAILS help you to identify and more fully optimize your lead formulations before you invest the time, money and safety effort required to place them in consumer tests.

VITRO-NAILS allow you to develop realistic in vitro tests to rapidly assess the performance of nail polish removers.

Publications
Presented at the Society of Cosmetic Chemists Annual Scientific Meeting, December 1998

A New Substrate for the Rapid, In Vitro Assessment of Nail Care Products
John P. Sottery, Ph.D. and Jorge H. Jaramillo
IMS Inc., Orange, CT 06477-3622 USA

Formulators around the world are working to deliver superior nail care products to consumers. Their efforts in this area would be greatly accelerated by the development of fast, reliable, in vitro methods to assess the performance of both nail enamels and nail polish removers. In the past, the development of these methods has been limited by the lack of a suitable substrate.

The goal of this research is to develop reliable in vitro nail methods that are predictive of the consumer perceived benefits. Our approach involves two phases: (1) the development of a reproducible, synthetic nail substrate that exhibits the wetting properties, thickness and flexibility of human nails, and (2) the development and validation of new in vitro methods based on this substrate. In this paper, we present preliminary results on a new synthetic nail substrate, as well as a new in vitro method to evaluate the durability of nail enamels.

A New Substrate for the Rapid, In Vitro Assessment of Nail Care Products (pdf – 350Kb)

Patents
Patents Referencing VITRO-NAILS® Substrate
Patent# Description Company
9,820,931 Latex Nail Compositions Having Low Amounts of Photo-initiator L’OREAL
9,649,272 Latex Nail Compositions Having Low Amounts of Photo-initiator L’OREAL
9,636,293 Latex Nail Compositions Having Low Amounts of Photo-initiator L’OREAL

Guarantee
VITRO-NAILS® – Unconditional Guarantee

Our No Hassle, 100% Satisfaction Guarantee: If for any reason you are not completely satisfied with the data you obtain using VITRO-SKIN®, VITRO-NAILS® or VITRO-CORNEUM®, simply return the unused substrate within 45 days for an immediate refund or credit.